I came across a post where the subject of the post looked 3d printed, but the first comment I came across was someone looking for the stl. Neither of us could find it, so I decided to fix that. 

I'm comfortable with Fusion 360 (even though my computer isn't), but the nature of the model got me to give Mesh Mixer a fair shake. I had a lot of fun learning, but I couldn't strike a balance between realism and printability. Instead, I just made both. There are a few (ultra low effort) FDM concessions in the extra realistic model, but I haven't tried printing it, because I'm sure the supports would be a nightmare. The easy print model came out pretty well in Atomic black marble PETG through a 0.8mm CHT nozzle. I put a lot of effort into getting contact with the build plate maximized and eliminating bridges and supports. Make sure you've got auto cooling enabled for the bridge of the skull (I didn't in my test print and it shows).

Again, this was my first shake at organic sculpting. Please feel free to improve the concept if you've got more experience. I had a lot of fun getting used to the sculpting tools, but I called it quits after 6 hours of trying to optimize the model (there are a few internal voids that shouldn't impact the print quality, but they do add to the final print time). The final product might need some adjustment to fit your glasses with a hot sculpting tool or suguru, but I did make some tweaks that should make them a bit more widely useable.

License permissions were retained from the original model.